期刊文献+

椎间盘切除术治疗腰椎间盘突出症腰痛的疗效观察 被引量:3

OUTCOME OF DISCECTOMY IN PATIENTS WITH LOW BACK PAIN ASSOCIATED WITH LUMBAR DISC HERNIATION
下载PDF
导出
摘要 目的:观察腰椎间盘突出伴有或不伴有腰椎退变Modic改变腰痛患者行椎间盘切除术后的疗效。方法:38例行椎间盘切除术的单节段椎间盘突出症腰痛患者,1组17例患者伴有腰椎退变Modic改变,包括8男,9女,平均年龄35.8岁(22~55岁),ModicⅠ型10例,ModicⅡ型7例。2组21例患者没有腰椎退变Modic改变,包括11男,10女,平均年龄35.5岁(21~60岁)。在术后3、6、12个月通过VAS疼痛评分评估疼痛改善情况,术后12个月通过JOA量表进行失能评估。结果:术前1组和2组VAS评分和JOA评分没有明显差异(P<0.05)。术后1组和2组患者腰痛和失能情况均明显改善(P<0.05)。在3、6、12个月,1组VAS评分分别是1.9±0.6、2.1±0.8和2.3±0.9,2组VAS评分分别是1.9±1.0、2.2±0.6和2.4±0.8;在术后12个月,1组和2组JOA评分分别是13.3±1.1和12.1±2.1,较术前明显改善(P<0.05)。结论:对于单节段伴有或不伴有Modic改变的椎间盘突出症腰腿痛患者,椎间盘切除术是一种良好的治疗方法。 Objective:To observe the outcome after lumbar discectomy in patients with disc herniation,concordant sciatica,and low-back pain with or without Modic degenerative changes Methods:Thirty-eight consecutive patients with single level disc herniation and low-back pain with Modic degenerative changes underwent fusion or lumbar dics neuclectomy.Group 1 consisted of 17 patients with Modic degenerative changes,8 men and 9 women,with a mean age of 35.8 years(range,22 to 55 y).Group 2 contained 21 patients without Modic degenerative changes,11 men and 10 women,with a mean age of 35.5 years(range,21 to 60 y).The visual analog scale(VAS) was used to grade low-back pain at 3,6,and 12 months and the Oswestry and JOA score were used to grade overall disability at 12 months postoperatively.Results:There was no significant difference in VAS and JOA scores for group 1 versus group 2 patients preoperatively.Average VAS scores of patients in group 1 were 1.9±0.6,2.1±0.8 and 2.3±0.9 at 3,6,12 months,VAS score in group 2 were 1.9±1.0,2.2±0.6 and 2.4±0.8 respectively.JOA scores in group 1 at 12 months were 13.3±1.1,the scores in group 2 were 12.1±2.1.The patients of both groups show significant improvement in postoperative JOA score(P0.05).Conclusions:Discectomy was an effective treatment for single level disc herniation and concordant sciatica and low-back pain with or without Modic I and II degenerative changes.
出处 《中国疼痛医学杂志》 CAS CSCD 2011年第3期137-140,共4页 Chinese Journal of Pain Medicine
关键词 椎间盘突出症 腰痛 椎间盘切除 MODIC 退变 Disc herniation Low back pain Fusion Discectomy Modic Degenerative
  • 相关文献

参考文献12

  • 1王非,瞿东滨,金大地.椎间盘软骨终板退变及其相关研究进展[J].中华骨科杂志,2003,23(9):544-546. 被引量:14
  • 2Ohtori S,Inoue G,Ito Tet al.Tumor necrosisfactor-immunoreactive cells and PGP 9.5-immuno-reactive nerve fibers in vertebral endplates of pa-tients with discogenic lowback pain and modic type1 or type 2 changes on MRI. SPINE . 2006
  • 3McCoy CE,Selby D,Henderson Ret al.Patientsavoiding surgery.Pathology and one-year life statusfollow-up. SPINE . 1991
  • 4Pearson AM,Blood EA,Frymoyer JW,et al.SPORTlumbar interverte-bral disk herniation and back pain:does treatment,location,or mor-phology matter. SPINE . 2008
  • 5Modic M T,Steinberg P M,Ross J S,et al.Degenerative disk disease: assessment of changes in vertebral body marrow with MR imaging. Radiology . 1988
  • 6Modic MT,Masaryk TJ,Ross JS,et al.Imaging of degenerative disk disease. Radiology . 1988
  • 7Weishaupt D,Zanetti M,Holder J,et al.Painful lumbar disk derangement: relevance of endplate abnormalities at MR imaging. Radiology . 2001
  • 8Gillet P.The fate of the adjacent motion segments after lumbar fusion. Journal of Spinal Disorders . 2003
  • 9Weber H.Lumbar disc herniation: a controlled, prospective study with ten years of observation. SPINE . 1983
  • 10Brown M F,Hukkanen M V J,McCarthy I D,et al.Sensory and sympathetic innervation of the vertebral endplate in patients with degenerative disc disease. Journal of Bone and Joint Surgery British Volume . 1997

二级参考文献25

  • 1董凡,戴克戎,侯筱魁.高应力环境导致腰椎软骨终板蛋白聚糖含量改变[J].中华骨科杂志,1997,17(2):127-129. 被引量:12
  • 2Kmppinen J,Paakko E,Raina S,et al.Magnetic resonance imaging findings in relation to the COL9A2 tryptophan allele among patients with sciatica.Spine,2002,27:78-83.
  • 3Sahlman J,Inkinen R,Hirvonen T,et al.Premature vertebral endplate ossification and mild disc degeneration in mice after inactivation of one allele belonging to the Col2al gene for type Ⅱ collagen.Spine,2001,26:2558-2565.
  • 4Furuya S,Ohtsuki T,Yabe Y,et al.Ultrastructural study on calcification of cartilage:comparing ICR and twy mice.J Bone Miner Metab,2000,18:140-147.
  • 5Lim TH,Kwon H,Jeon CH,et al.Effect of endplate conditions and bone mineral density on the compressive strength of the graft-endplate interface in anterior cervical spine fusion.Spine,2001,26:951-956.
  • 6Steffen T,Tsantrizos A,Aebi M.Effect of implant design and endplate preparation on the compressive strength of interbody fusion constructs.Spine,2000,25:1077-1084.
  • 7Wehling P,Schulitz KP,Robbins PD,et al.Transfer of genes to chondrocytic cells of the lumbar spine:proposal for a treatment strategy of spinal disorders by local gene therapy.Spine,1997,22:1092-1097.
  • 8Panjabi MM,Chen NC,Shin EK,et al.The cortical shell architecture of human cervical vertebral bodies.Spine,2001,26:2478-2484.
  • 9Edwards WT,Zheng Y,Ferrara LA,et al.Structural features and thickness of the vertebral cortex in the thoracolumbar spine.Spine,2001,26:218-225.
  • 10Chandraraj S,Briggs CA,Opeskin K.Disc herniations in the young and end-plate vas cularity.Clin Anat,1998,11:171-176.

共引文献13

同被引文献19

引证文献3

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部