常见食物中毒质谱图数据库系统平台建设

Mass spectrum database system for food poisoning substances

食物中毒事件具有群发性、复杂性、突发性和危害严重等特点,确证引起食物中毒的病因对食物中毒事件处理具有现实意义。色谱质谱联用系统作为国际上通用的未知物质快速检测及确认手段被广泛的应用于未知物质的检测及确认领域中,质谱图数据库系统是应用质谱方法确认中毒物质的关键系统,针对食物中毒的特点,开发了常见食物中毒质谱图数据库系统。系统采用流行的B\S三层结构,数据库可以存储不同仪器以不同采集方式采集的质谱图数据,同时还加载了相关化合物的理化性质、毒理学资料和临床症状等信息;并通过网络实现应急平台的资源共享,同时具有质谱谱图的快速搜索功能,为不明原因食物中毒辅助诊断提供重要的技术措施,为大规模食物中毒的预警提供重要信息,为突发公共卫生事件应急反应机制提供决策支持。

Mass food poisoning affair is really challenging to our society.Which usually outburst,complex and generally having severity result. Identify the cause of food poisoning affair is important for handle such emergency.The general methods for identifying unknown substances is Gas chromatography-mass spectrometry or liquid chromatography-mass spectrometry.Food poisoning substances Mass spectrum database is a critical tool for use mass spectrometry method identifying the substances which cause the poisoning affair,Food poisoning substances mass spectrum database system take three layer Browser／Server structure.Which can storage mass spectrum from different mass collection modes,and which also contain the corresponded data like physical chemistry property,toxicological.The mass spectrum database share it＇s data via Internet.Which also provide mass spectrum fast search function,food poisoning substance mass spectrum can provide valuable information for mass food poisoning handling.