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中国西北汉族人群HLA-A^＊02等位基因的分布特点 被引量：1

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摘要 目的研究西北汉族人群HLA-A* 02等位基因的分布特点。方法对760份健康无血缘关系的西北汉族人群HLA-A* 02等位基因进行高分辨基因分型,计算HLA-A* 02各等位基因构成比并与其他不同地区人群进行比较。结果 760份样本中,检出9种HLA-A* 02等位基因,以A* 0201(48.86%)为优势等位基因,A* 0207(22.72%)和A* 0206(15.91%)比较常见,纯合子主要为A* 0201/A* 0201,杂合子主要为A* 0201/A* 0207。结论西北汉族人群HLA-A*02等位基因的分布特点比较接近北方汉族人群,但具有其自身分布特点。
作者 李国英 王明禄 刘圆圆 唐朝晖 杨勇毅 李元荣
机构地区 甘肃省红十字血液中心
出处 《中国输血杂志》 CAS CSCD 北大核心 2011年第3期237-238,共2页 Chinese Journal of Blood Transfusion
关键词 人类白细胞抗原(HLA) HLA-A^＊02等位基因 基因测序分型
分类号 R392.2 [医药卫生—免疫学] R457.11 [医药卫生—治疗学]
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共引文献59

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中国输血杂志
2011年 第3期

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