肺毒清冲剂抗病毒实验研究

Experimental Study on Antiviral Effect of Feiduqing Granules

目的 :观察肺毒清冲剂的抗病毒作用。方法 :体外抗病毒实验采用鸡胚法 ,以血凝反应为测定指标。体内抗病毒实验以病毒滴鼻法感染小鼠 ,观察肺毒清对肺指数、肺部病变程度的影响。结果 :肺毒清冲剂在药物浓度为 1∶10 0时可完全阻止流感病毒感染鸡胚。并且该方能抑制仙台病毒感染小鼠肺指数的升高 ,减轻肺部的病变程度。结论

OBJECTIVE: To observe antiviral effect of Feiduqing Granules. METHOD: In vitro, the hemagglutination reaction of Feiduqing Granules were tested in the chicken embryo culture. In vivo, the influences on lung index and pulmonary consolidation was observed in the mice infected with virus from nose. RESULT: Feiduqing Granules with concentration of 1∶100 completely prevented influenza virus infecting chicken embryo, decreasd lung index in mice infected with Sendai virus and reduced the pulmonary consolidation degree. CONCLUSION: Feiduqing Granules had a good antiviral effect.