肺炎支原体感染和小儿支哮喘的关系研究

Study on the relationship between bronchial asthma in children and mycoplasma pneumonia(MP) infection

目的:探讨小儿支气管哮喘与肺炎支原体(MP)感染的关系。方法:儿童哮喘专科门诊及住院哮喘发作期患儿386例(哮喘组)及同期就诊的呼吸道感染患儿426例(对照组),采用MP被动冷凝集法检测血清肺炎支原体抗体(MP-Ab)。结果:哮喘组MP-Ab阳性186例,阳性率48.2%,对照组阳性106例,阳性率25.8%,两组比较差异显著(P<0.01)。结论:MP感染与儿童哮喘关系密切,MP导致呼吸道慢性炎症,进而改变呼吸道高反应性是最根本的机制。对哮喘发作期的患儿要考虑MP感染可能,应常规行MP-Ab检查。

Objective：To discuss the relationship between bronchial asthma in children and mycoplasma pneumonia（MP） infection.Methods： All the 386 cases of paroxysmal asthma（bronchial asthma group） from our hospital were selected.426 children with respiratory tract infection served as control group.MP-Ab was detected by CAT method in both groups.Results： MP-Ab was postive in 186cases（48.2%）in bronchial asthma group;106 cases（25.8%） in control group.There was a significant difference between the two groups（P0.01）.Conclusion： There is a close relationship between MP infection and children bronchial asthma.The estivity of respiratory tract.The possibility of MP infection should be taken into account while treating children with paroxysmal asthma.MP-Ab should be detected routinely in children with paroxysmal asthma.