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头孢洛林酯(ceftaroline fosamil) 被引量:4

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摘要 头孢洛林酯(ceftaroline fosamil)由日本武田制药(Takeda Pharmaceutical)公司开发,美国Forest Laboratories (Cerexa)公司获得市场授权,于2010年10月29日经美国药品食品管理局批准上市。该药商品名为Teflaro,是头孢洛林的前药(即N-磷酰化头孢洛林)。
作者 高健 孙铁民
机构地区 沈阳药科大学
出处 《中国药物化学杂志》 CAS CSCD 2011年第2期167-168,共2页 Chinese Journal of Medicinal Chemistry
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参考文献4

  • 1ISHIKAWA T, MATSUNAGA N, TAWADA H, et al. TAK- 599, a novel N-phosphono type prodmg of anti-MRSA cepha- losporin T-91825 : synthesis, physicochemical and pharmaco- logical properties [ J ]. Bioorg Med Chem, 2003,11 ( 11 ) : 2427 - 2437.
  • 2ISHIKAWA T, HASHIGUCHI S, IIZAWA Y. Phosphono- cephem compound :WO,0214333 [ P]. 2002 - 02 - 21.
  • 3STEED M E, RYBAK M J. Ceftaroline:a new cephalosporin with activity against resistant gram-positive pathogens [ J ]. Pharmacotherapy,2010,30(4) :375 -389.
  • 4ZHANEL G G, SNJEZEK G, SCHWEIEER F. Ceftaroline: a novel broad-spectrum cephalosporin with activity against meti-cillin-resistant Staphylococcus aureus [J]. Drugs, 2009, 69 (7) :809 -831.

同被引文献58

  • 1Wang Y, Serradell N, Rosa E, et al. Ceftaroline fosamil. Cephalospo- tiomtibiotic[J]. Drugs Fut, 2008, 33(4): 302-309.
  • 2Goto J, Sakane K, Teraji T. Studies of(aminoaryl)aeetami- halosporin derivatives. Ill.Synthesis and structure-activity :i,~nships in the aminothiadiazole series[J]. J Antibiot, 1984, 37 557-571.
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  • 6Takeo K, Keizo T,Yasuhide T, et al. Thiadiazolylacetamide deriva- tives, process for the preparation thereof and their use[P].EP: 0248434, 1987-12-09.
  • 7Kanai T, Takayanagi K, Tanaka Y. Preparation of 1,2,4-thiadiazol (alkoxyimino)acetic acids as intermediates for cephalosporins[P].dP: 62286979, 1987-12-12.
  • 8Poon H, Chang M H, Fung H B. Ceftaroline fosamil: a cephalosporin with activity against methicillin-resistant Staphylococcus aureus[J]. Clin Ther, 2012, 34(4): 745-765.
  • 9McCaig L F, McDonald L C, Mandal S, et al. Staphylococcus aureus-associated skin and soft tissue infections in ambulatory care[J]. Emerg lnfect Dis, 2006, 12(11): 1715-1723.
  • 10Talbot G H, Thye D, Das A, et al. Phase 2 study of ceftaroline versus standard therapy in treatment ofcomplicated skin and skin structure infections[J]. Antmicrob Agents Chemother, 2007, 51(10): 3612-3616.

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