2007～2009年广州部分人群肝吸虫病感染状况血清学分析

Serological analysis of Clonorchis sinensis infection in partial population of Guangzhou City from 2007 to 2009

目的了解广州地区人群肝吸虫感染状况。方法应用ELISA法检测健康体检人群的肝吸虫抗体。结果三年共检测14 600例,其中肝吸虫抗体阳性1 669例,阳性率为11.4%,并呈逐年上升趋势。其中男性阳性率为13.0%(1 242/9 530),女性8.4%(427/5 070),男女之间差异有统计学意义(P=0.000)。结论广州地区人群中肝吸虫感染率逐年升高,且男性感染率显著高于女性,应加强健康人群肝吸虫病的监测,开展卫生教育,防止经口感染,以有效控制正常人群肝吸虫的感染。

Aim To understand the infectous status of partial population with Clonorchis sinensis in guangzhou and provide the scientific basis for clinical diagnosis and control of the parasite.Methods The antibody against Clonorchis sinensis in healthy population was examined by using enzyme-linked immunosorbent assay.Results 14 600 cases were tested and 11.4% of them were positive for Clonorchi sinensis.The positive rates in males and females were13.0% and 8.4%,respectively,showing showing significant difference（P=0.000）.Conclusion Integrated control mesuers be enfored in this area including health education,monitoring of the infectious status of the population for effective control the infection of the parasites.