济宁市2009年流感样病例暴发疫情特征分析

Features of outbreak of influenza-like infection in 2009 in Jining

目的了解济宁市流感样病例暴发疫情特征,为科学防控流感提供参考依据。方法回顾性分析济宁市2009年流感样病例暴发疫情资料。结果济宁市2009年累计报告流感样病例暴发疫情22起,累计发病人数554例,平均罹患率为1.67%。全市12县市区中有8个有流感样病例暴发疫情报告,18起（81.82%）发生于9~12月;21起（95.45%）发生于中、小学生人群;14起（63.64%）疫情发病人数规模在30例以下。流感样病例暴发疫情主要由甲型流感病毒（81.82%,18/22）引起。所有甲乙型流感PCR检测的阳性标本均立即接种MDCK细胞进行病毒分离培养,共分离流感病毒15株,溯源于5起疫情（5/222,2.73%）,其中1起为H3N2亚型、4起为新甲型H1N1亚型。自9月份始明显升高9,月份上中旬以季节性甲3流感暴发为主,9月份下旬以后以新甲型H1N1流感为主,秋冬季为暴发高峰。结论济宁市2009年流感样病例暴发疫情主要由甲型流感病毒引起,主要发生于9～12月,学校是全市流感暴发疫情防控工作的关键所在。

Aim To understand the features of outbreaks of influenza-like illness（ILI） in Jining,and provide evidence for scientific prevention and control of the disease.Methods Restrospective analysis of data of outbreaks of ILI in Jining was performed.Results There 22 outbreaks of ILI were reported,cumulative numbers of ILI were 554,with an incidence of 1.67%.18 cases（81.82%） of the ILI occurred from September to December;21cases（95.45%） occurred in primary schools and middle schools;There 81.82% outbreak were due to influenza A virus infection.All positive samples detected by PCR were immediately inoculated with MDCK cells for virus isolation and culture and 15 strains were isolated from 5 cases including one subtype H3N2 and fourinfluenza A virus subtype H1N1.The infections Increased significantly since the beginning of September and mainly concentrated in autumn and winter.Conclusion Influenza-like illness are mainly due to influenza virus infection and the infections mainly concentrated in the months from September to December.Primary schools and middle schools are the target for prevention and control of outbreaks of influenza in Jining.