摘要
铜绿假单胞菌可以产生多种毒力因子，是引起细菌慢性持续感染的重要原因之一。其密度感应系统与其毒力因子的合成密切相关。近年，有大量研究发现其分泌的毒力因子可以影响宿主的免疫系统，产生致病作用。因此，现在就毒力因子的致病作用的相关研究作一综述。
Pseudomonas aeruginosa can produce a variety of virulence factors, which is one of the important reasons of chronic persistent bacteria infection. The quorum-sensing system of Pseudomonas aeruginosa is closely related to synthesis of virulence factors. In recent years, numerous studies have found that the virulence factors secreted can influence the host immune system, result in pathogenicity. So this review focuses on the related researches about pathogenicity of virulence factors.
出处
《国际呼吸杂志》
2011年第8期612-615,共4页
International Journal of Respiration
关键词
铜绿假单胞菌
密度感应系统
毒力因子
Pseudomonas aeruginosa
Quorum-sensing system
Virulence factor
