壳聚糖宫颈抗菌膜用于高频电波刀宫颈疾病治疗的观察

Clinical effect of chitosam in LEEP on the treament for cervical diseases

目的：观察壳聚糖宫颈抗菌膜在高频电波刀（LEEP）治疗宫颈疾病的疗效及安全性.方法：将本院2005年1月-2007年1月宫颈疾病治疗中心,242例宫颈疾病,经LEEP治疗后的患者随机分成两组,一组子宫颈使用壳聚糖抗菌贴膜 另一组不使用任何药物进行治疗,分别对其术后阴道排液,阴道流血,创面愈合情况进行观察.结果：观察组阴道流血量及阴道流血时间,阴道排液少于对照组,4周内观察组发现阴道炎患者数明显少于对照组.观察组创面愈合快.结论：壳聚糖宫颈抗菌膜可减少LEEP治疗宫颈疾病术后出血及感染,有助于创面修复,其用于LEEP治疗宫颈疾病术后是安全的.

Objective：To study the clinical effect and safety of cervical antibacterial chitosan film in the loop electrosurgical excision procedure （LEEP） treatment for cervical diseases. Methods： 242 cases with cervical diseases underwent LEEP during January 2005 and January 2007 ijn our department were randomly divided into experimental group undertaking Chistosan and control group without any medication. The postoperative vaginal discharge, vaginal bleeding volume and cervical wound healing were studied. Results：Patients in experimental group were with less vaginal bleeding volume, shorter bleeding time and less vaginal discharge. It was observed that vaginitis cases within 4 weeks after operation in experimental group were significantly less than that of control group. ＂Wound healing was faster in experimental group. Conclusion： Chitosan is a safe in LEEP treatment for cervical diseases since it may reduce postoperative bleeding and infection, and may help in cervical wound healing.