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脂滴包被蛋白(perilipin)研究进展 被引量:1

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摘要 脂滴是脂肪细胞的主要成分,它占据了脂肪细胞的大部分空间,是中性脂质的主要贮存场所。脂滴包被蛋白(perilipin)作为一种重要的脂肪代谢相关蛋白包被于脂滴的表面.perilipin在脂肪代谢调控中起到“分子开关”的作用,对脂滴的代谢具有重要的调控作用。然而perilipin的表达和活性又受到很多因素的调控,如肿瘤坏死因子(TNF—α)、过氧化物酶体增殖物激活受体(PPARγ)、瘦素(leptin)等等均可以影响perilipin的表达。研究表明,Perilipin基因多态性与背膘厚、日增重、脂肪沉积等性状相关。
出处 《河南畜牧兽医(综合版)》 2011年第4期10-11,共2页 Henan Journal of Animal Husbandry and Veterinary Medicine
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