期刊文献+

小檗碱对中枢神经系统相关疾病治疗研究进展 被引量:9

下载PDF
导出
摘要 小檗碱又称黄连素,临床上主要用于治疗胃肠道疾病。研究显示,小檗碱还具有抗菌、降血糖、治疗心血管系统疾病,抗肿瘤等多种药理活性。随着对小檗碱研究的深入,关于其对中枢神经系统相关疾病治疗潜力越来越受到关注。
作者 王静 张艳军
出处 《天津中医药》 CAS 2011年第2期173-174,共2页 Tianjin Journal of Traditional Chinese Medicine
基金 教育部科学技术研究重点项目(208009) 高等学校博士学科点专项科研基金(20101210110001)
  • 相关文献

参考文献4

二级参考文献58

  • 1魏佑震,姚志彬,袁群芳,陈以慈.小檗碱对大鼠全脑缺血后海马的保护作用[J].神经解剖学杂志,1995,11(4):315-321. 被引量:14
  • 2吴俊芳,史以菊,刘天培.小檗碱对小鼠和大鼠脑缺血的保护作用[J].中国药理学与毒理学杂志,1995,9(2):100-103. 被引量:70
  • 3林媛,张世平,吕俊华.小檗碱对D-半乳糖诱导糖基化模型大鼠脑损害的干预作用(英文)[J].中国临床康复,2006,10(43):200-203. 被引量:2
  • 4Kim TS,Kang BY, Cho D, et al. Induction of interleukin-12 production in mouse macrophages by berberine, a benzodioxoloquino lizine alkaloid, deviates CD^4+ T cells from a Th2 to a Tbl re sponse. Immunology,2003,109(3) :407 414.
  • 5Kim JS, Gautam SC, Chopp M, et al. Expression of monocyte chemoattractant protein and macrophage inflammatory protein-1 after focal cerebral ischemia in the rat J Neuroimmunol, 1995,56 (2), 127-134.
  • 6Gourmala NG,Buttini M, Limonta S,et al. Differential and time-dependent expression of monocyte chemoattractant protein-1 mRNA by astrocytes and macrophages in rat brain: effects of ischemia and peripheral lipopolysaccharide administration. J Neuroimmunol, 1997,74 (1-2) : 35 44.
  • 7Che X, Ye W, Panga L, et al. Monocyte chemoattractant protein 1 expressed in neurons and astrocytes during focal isehemia in mice. Brain Res,2001,902(2) : 171-177.
  • 8Wang F, Zhao G,Cheng L, et al. Effects of berberine on potassium currents in acutely isolated CA1 pyramideal neurons of rat hippocampus. Brain Res, 2004,999( 1 ) : 91-97.
  • 9Yoo KY, HWANG IK, LIM Bo, et al. Berberry ectract reduces neuronal damage and N-Methy-D-aspartate receptor 1 immunoreactivity in the gerbil hippocampus after transient forebrain ischemia. Biol Pharm Bu11,2006,29(4):623-628.
  • 10Chan PH, Kawase M, Murakami K, et al. Overexpression of SOD1 in transgenic rats protects vulnerable neurons against ischemic damage after global cerebral isehemia and reperfusion. J Neurosci, 1998, 18 (20) : 8292-8299.

共引文献12

同被引文献133

引证文献9

二级引证文献83

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部