摘要
目的评价坦索罗辛与哌替啶联用治疗肾绞痛的效果。方法按就诊顺序将急性肾绞痛122例随机分为观察组和对照组(每组61例),观察组给予坦索罗辛口服加哌替啶肌内注射,对照组给予阿托品、哌替啶肌内注射,比较两组药物镇痛效果及不良反应。结果观察组有效58例,无效3例,有效率为95.1%,未见明显不良反应。对照组有效44例,无效17例,有效率为72.1%(P<0.01);心动过速4例,口舌干燥难忍28例,排尿困难7例,出现不良反应的患者予平卧休息、补液、饮水和保留导尿后缓解。观察组显示了较好的镇痛效果而不良反应较小。结论坦索罗辛加哌替啶治疗急性肾绞痛显效快、缓解率高、不良反应小。
Objective To evaluate the therapeutic effect on nephrocolic with tamsulosin and meperidine.Methods 122 patients with nephrocolic were divided into test and control group（each group had 61 cases）.Tamsulosin and pethidine were orally administrated to test group,and atropine and pethidine were administered by intramuscular injection.The effect of relive pain in patients and side effect were compared between two groups.Results 58 cases（95.1%） were remittenced in test group,while 44 cases（72.1%） were in control group（P〈0.01）.The test group had no severity untoward effects.Conclusions Tamsulosin hydrochloride and meperidine therapia nephrocolic better than atropine and meperidine,because it had the features of high remission rate,fewer dosage,diminutive side effect.
出处
《东南国防医药》
2011年第2期128-129,156,共3页
Military Medical Journal of Southeast China
关键词
肾绞痛
治疗
临床研究
坦索罗辛
nephrocolic
therapeutics
clinical research
tamsulosin
