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心肌缺血预适应在急性心肌梗塞中的临床意义 被引量:1

Clincal significance of ischemic preconditioning in acute myocardial infarction
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摘要 目的探讨心肌缺血预适应在急性心肌梗塞中的临床意义。方法58例AMI患者分为梗塞前24h内有心绞痛组35例,梗塞前24h内无心绞痛组23例。入院后按统一方案治疗,观察比较两组的心肌酶峰值、严重心律失常发生率及院内死亡率。结果有梗塞前心绞痛组心肌酶峰值、严重心律失常发生率及院内死亡率显著低于无梗塞前心绞痛组(P<005)。结论梗塞前有心绞痛发作能有效的诱导缺血预适应,对心肌起保护作用,使心肌梗塞面积缩小,心律失常发生率及死亡率降低。 Objective To estimate the clincal significance of ischemic preconditioning in acute myocardial infarction MethodsFifty-eight of AMI patients were divided into tow groups according to the occurrance of angina pectoris(AP) 24 hours before AMI, one group are 35 cases who has AP,the other group in 23 cases without APBoth goup were treated with the same methods and the peak values of myocardial enzyme,the incidence of severe arrhythemia and mortality of hospital were observed Results The peak values of myocardial enzyme,the incidence of severe arrhythemia and mortality of hospital in group 1 is very lower than that of group ConclusionThe patiets with occurance of angina pectoris before infarction by precondioning can result and reduce the size of infarction,incidence of arrythmia and mortality
出处 《新乡医学院学报》 CAS 1999年第2期127-128,共2页 Journal of Xinxiang Medical University
关键词 缺血预适应 急性 心肌梗塞 临床意义 ischemic proconditioning acute myocardial infarction clinic signficance
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