椎体终板形态与腰椎间盘突出关系的临床研究(英文)

Clinic research between vertebral endplate morphology and lumbar disc herniation

背景:有研究报道,在间盘退变的过程中,可造成椎体终板的重塑。目前终板形态和椎间盘退变的关系仍不非常清楚。目的:观察分析椎体终板形态与腰椎间盘突出症的之间的关系。方法:纳入40例无腰椎疾病的正常人和62例腰椎间盘突出症患者,进行螺旋CT扫描,扫描范围从L4到S2,扫描条件:140kV,345mA,FOV160mm,层厚1mm,间距1.0。原始图像通过O2的三维重建图像工作站进行三维重建,W300,C80,ZOOM=1.5,Expand1。在平面重建术(CPR)基础上测量椎间盘最大前后,横径,圆形,面积和形状。结果与结论:终板形态和椎间盘突出症密切相关(P均<0.01)。终板面积和男性L4/5、男性和女性的L5/S1椎间盘突出关联差异无显著性意义(P<0.05)。提示椎体终板的边缘形状是腰椎的椎间盘突出症(L4/5、L5/S1)进展的重要因素之一。

BACKGROUND：Studies demonstrated that vertebral endplate can be remodeled during intervertebral disc degeneration.However,the relationship between morphology of the vertebral endplate and intervertebral disc degeneration remains poorly understood.OBJECTIVE：To explore the relationship between the morphology of the vertebral endplate and the lumbar disc herniation.METHODS：Forty cases without previous spine disorder and sixty-two cases symptomatic lumbar disc herinations lumbar vertebral were scanned by using spiral CT.Scan range was from superior L4 to superior S2.Scan protocols as below：140 kV,345 mAs,FOV 160 mm,layer of thick 1 mm,pitch 1.0.Original images were carried through three-dimensional reconstructions using O2 image work station,W300,C80,ZOOM=1.5,Expand 1.Intervertebral disc maximum anteroposterior,transverse diameter,circumference,area and shape were measured based on curve planar reconstruction.RESULTS AND CONCLUSION：Endplate shape was strongly related to disc herniation（all the P value 0.01）.Endplate area was a less significant factor L4/5 in men and L5/S1 in men and females（P 0.05）.The shape of the intervertebral body endplate margin is an important factor contributing to the development of disc herniation at L4/5 and L5/S1.