放化疗配合中医辨证治疗脑转移瘤临床观察

Clinical Observation on Radio or Chemotherapy plus Traditional Chinese Medicine in Treating Brain Metastic Tumor

目的：观察放化疗配合中医辨证治疗脑转移瘤临床疗效。方法：６７例患者随机分为化疗配合中药组（观察Ⅰ），放疗配合中药组（观察Ⅱ）与单纯化疗组（对照Ⅰ），单纯放疗组（对照Ⅱ），对４组疗效作比较观察。结果：观察Ⅰ、Ⅱ组患者近期有效率（完全缓解加部分缓解）、生存质量、１～４年生存率及中位生存时间、部分免疫功能指标明显高于对照Ⅰ、Ⅱ组（Ｐ＜００５）。结论：放化疗配合中医辨证治疗脑转移瘤，具有抑制肿瘤生长，延长生存时间，提高生存质量之效。

Objective: To observe the clinical efficacy of radio or chemotherapy plus traditional Chinese medicine (TCM) by Syndrome Differentiation in treating brain metastic tumor. Methods: Forty one patients were randomized into four groups: Group A treated with chemotherapy plus TCM, Group B with radiotherapy plus TCM, Group C with chemotherapy alone and Group D with radiotherapy alone. The efficacies of the four groups were compared. Results: The short term response rate, living quality, 1 ,2 ,3 and 4 year survival rate, median survival period and immunity of the Group A and B were significantly higher than those of the Group C and D (P<0 05). Conclusion: Radio or chemotherapy plus TCM by Syndrome Differentiation has the effect of tumor growth inhibition, survival period extension and living quality enhancement in treating brain metastases.