中药加克罗米芬与克罗米芬加hMG诱导排卵疗效的比较

A Comparision of CTM+Ciomiphene and Clomiphene+hMG on Ovulation Induction

19例排卵功能障碍患者分别采用中药加克罗米芬和克罗米芬加hMG诱导排卵,两组均采用动态B超监测卵泡发育和血清生殖激素放射免疫测定。5例排卵功能正常妇女为正常对照组。结果:中药加克罗米芬组与克罗米芬加hMG组诱导排卵率分别为90％、100％,受孕率为50％、22.2％;两组排卵率与受孕率之间差异无显著意义;两组排卵前平均最大卵泡直径和E_2峰值之间差异均无显著意义;而且中药加克罗米芬治疗,价廉、副作用小。

A combined treatment of Chinese Traditional.Medicine (CTM) and clomiphene was used in 10 ovulatory defective patients.The regimen was compared with the treatment of 9 cases treated with clomiphene+hMG by continuous investigation of E2,P,LH levels and B-model ultrosonography pre-and post-treatment.Five normal ovulatory women were selected as normal controls.The results showed that the ovulatory rates were 90% and 100% respectively (P>0.05).The one course conceive rates were 50% and 22.4% respectively (P>0.05).The largest follicular diameters of these three groups were 23.6±5.3 mm,24.1+3.1 mm and 18.4±0.89 mm respectively.The peak value of E2 was significantly higher in the two stimulated groups (P<0.05),but no significant difference was noted between the two treated groups (P>0.05).