枳壳旋复花乌药汤剂治疗术后胃功能性延迟排空症31例

Treatments with decoction composed of fructus aurantii,inula japonica,and lindera strychnifolia for 31 cases with syndrome of postoperative functional delayed gastric empty

目的：观察中药枳壳旋复花乌药汤剂对术后胃功能性延迟排空症的治疗效果。方法：术后胃功能性延迟排空症患者３１例，随机分为２组。在西医综合治疗基础上，中药治疗组（２１例）采用枳壳旋复花乌药汤剂胃管注入，每日４次；胃复安治疗组（１０例）采用胃复安１０ｍ肌注，每６小时１次。观察治疗后患者的腹胀感觉、肠鸣音、胃蠕动次数、胃肠减压量和血电解质恢复情况。结果：２组治愈时间〔中药治疗组（１８．６±３．２）日，胃复安治疗组（１９．９±４．３）日〕相近，Ｐ＞０．０５；患者的腹胀感觉、治疗后１小时肠鸣音、胃蠕动、血电解质平衡情况２组疗效相近，但是中药组治疗后５小时肠鸣音恢复情况（８５．７％）、胃肠减压引流液减少量〔（６００±９７）ｍｌ〕优于胃复安治疗组〔６０．０％及（４００±８０）ｍｌ，Ｐ均＜０．０５〕。结论：枳壳旋复花乌药汤剂是治疗术后胃功能性延迟排空症的有效药物，其促进胃肠排空功能的作用较胃复安持久，减少胃肠液丢失量优于胃复安，有利于维持水。

Objective:To observe the curative effects of decoction composed of fructus aurantii,inula japonica,and lindera strychnifolia on syndrome of postoperative functional delayed gastric empty(PFDGE).Methods:31 cases with PFDGE were randomly divided into two groups.Based on general western medicine therapy for two groups,in the traditional Chinese medicine (TCM) group ( n =21) decoction composed of fuctus aurantii,inula japonica,and lindera strychnifolia was given via nasogastric tube four times a day,and in the metoclopramide group ( n =10) metoclopramide 10 mg injected intramuscularly once per 6 hours.After therapy the patients′ feeling of abdominal flatulence,bowel sound,times of gastric peristalsis,volume of gastrointestinal depressing pressure,and concentrations of serum electrolytes were observed.Results:The duration for cured was similar in TCM group (18 6±3 2)days and metoclopramide group (19 9±4 3)days respectively ( P >0 05),meanwhile the curative effects on abdominal flatulence,bowel sound in 1 hour after therapy,gastric peristalsis,and conditions of serum electrolyte balance were similar too.Otherwise in TCM group in 5 hours after therapy the recovering conditions of bowel sound (85 7%) and the reduced volume of gastrointestinal depressing pressure (600±97)ml were superior to those 60 0% and (400±80)ml respectively in metoclopramide group significantly (all P <0 05).Conclusions:The decoction composed of fructus aurantii,inula japonica,and lindera strychnifolia are effective in treating PFDGE and the action on the function of promoting gastric empty is longer than that of metoclopramide and for reducing the loss of gastrointestinal juice.It is beneficial to keeping serum electrolyte balance and recovering gastrointestinal functions.