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罗格列酮对老年2型糖尿病患者颈动脉硬化的影响 被引量:2

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摘要 目的:探讨罗格列酮对老年2型糖尿病(T2DM)患者颈动脉硬化的影响。方法:将76例合并颈动脉硬化的T2DM患者随机分为观察组和对照组,每组各38例。对照组予格列比嗪、二甲双胍药物治疗,观察组在对照组治疗基础上给予罗格列酮4m g/d。治疗前及治疗后6个月分别检测血脂水平,采用超声多普勒检测双侧颈动脉内中膜厚度(IMT)和管腔内径。结果:罗格列酮治疗6个月后,观察组TG水平明显降低,HDL-C水平明显升高,与治疗前和对照组比较,差异有统计学意义。观察组颈动脉IMT变薄,管腔内径增大,与治疗前和对照组比较,差异有统计学意义。结论:罗格列酮能改善血脂,延缓颈动脉粥样硬化进展。
出处 《陕西医学杂志》 CAS 2011年第4期441-442,476,共3页 Shaanxi Medical Journal
基金 沈阳市科学技术技划项目(1071162-9-00)
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