摘要
目的研究鼻局部吸入布地奈德治疗过敏性鼻炎对哮喘发作的影响。探讨患者用布地奈德治疗过敏性鼻炎对哮喘症状及肺功能变化的影响。方法采用临床试验方法研究门诊63例支气管哮喘合并过敏性鼻炎患者。随机分为布地奈德组(30例)和对照组(33例)。所有患者均规律经口吸入哮喘常规药物,布地奈德组规律加用鼻吸布地奈德。随访12周后再次进行研究,比较患者哮喘症状以及肺功能变化。结果布地奈德组在经过鼻吸布地奈德12周后与对照组ACT记分和肺功能比较有统计学意义(P<0.01)。2组在治疗前的差异无统计学意义(P>0.05)。结论过敏性鼻炎是哮喘发病的危险因素,鼻局部吸入布地奈德治疗伴有轻、中度哮喘的过敏性鼻炎患者,当鼻炎症状改善的同时,哮喘症状亦获得缓解,气道反应性降低。
Objective To study the influence of nasal glucocorticoid inhalation on allergic rhinitis complicated with asthma.To exploring the effect of rhinocort in allergic rhinitis on asthmatic symptom and variation of lung function.Methods 63 cases of outpatients suffered from allergic rhinitis comolicated with bronchial asthma were investigated in clinical method.They were divided into the rhinocort group（30 cases） and control group（33cases） randomly.All the people inhaled routine asthmatic medicine regularly.The rhinocort group add nasal rhinocort inhalation.Two groups were observed for 12 weeks.After 12 weeks,they were observed again from the symptom of asthma and the variation of lung function.Results There were statistical difference in the symptom of asthma and the variation of the lung function between the rhinocort group and the contronl group after 12 weeks（P0.01）.However there were no statistical difference between the two groups at the begin of the treatment（P0.05）.Conclusion Allergic rhnitis is a risk factor in the attack of asthma.Nasal inhalation of rhinocortcan improve the asthmatic symptoms and pulmonary function for patients with allergic rhinitis complicated by airway resistance or asthma.
出处
《中外医疗》
2011年第8期20-21,共2页
China & Foreign Medical Treatment
