无精子症的病因分析

Etiological analysis of azoospermia

目的：对无精子症的病因进行分析。方法：对本院收治的１５０ 例无精子症患者进行回顾性研究，根据体检第二性征是否正常、两侧睾丸体积大小是否均匀、生殖激素测定正常与否，以初步鉴别是输精管阻塞性无精子症还是睾丸源性无精子症，然后作进一步相关检查，明确梗阻或生精障碍的确切病因。结果：输精管阻塞及缺如 ４１ 例，占２７．３％ ；生精障碍 １０４ 例，占６９．３％ ；原因不明 ５例，占３．４％ 。结论：通过对无精子症病因的分析，可以最大限度地筛选出用手术或药物可治愈的病例。

Purpose: To investigate the etiology of azoospermia. Methods: 150 male married patients, being 25 to 45 years old with average age 28.5, had no birth for 2 to 21 years with mean 5 years, and no spermatozoa observed in more than twice semen analyses. Dependent on physical examination on second sexual signs, bilateral testes dimension and levels of sexual hormones, these patients were initiatively differentiated into ductal obstructive azoospermia or testicular azooospemia, and further determined their obstructive location and etiology of seminiferous dysfuction by related test. Results: We observed 41 cases ( 27.3 %) of occlusion and agenesis of deferent duct,104 cases ( 69.3 %) seminiferous dysfunction and 5 cases ( 3.4 %) idiopathic azoospermia. Conclusions: By the comprehensive analyses of the pathologic courses of azoospermia, some cases of azoospermia suitable for surgical intervention could be selected out to the uttermost limit, especially for medical treatment.