盐酸戊乙奎醚注射液与山良菪碱抗休克作用的对比研究

Comparision of the antishock effect between penequuiine hydrochloride and anisodamine

目的观察盐酸戊乙奎醚(长托宁)对于休克的治疗作用。方法 67例休克患者按就诊日期随机分为长托宁组和山崀菪碱(654-2)组。除常规抗休克治疗外,长托宁组另予长托宁治疗,而654-2组予山良菪碱治疗。监测治疗后1、6、12 h患者心率、血压、中心静脉压、肠鸣音、尿量、指脉氧饱和度、末梢转暖持续时间和血乳酸的变化。结果长托宁组的上述指标改善明显优于654-2组。结论盐酸戊乙奎醚的抗休克作用优于山崀菪碱。

Objective To study the therapeutic effect of penequinine hydroehloride （PH） on the shock. Methods According to the date of visiting hospital, 67 patients with shock were ramdomly divided into two groups： PH group and 654-2 group. In addition to routine therapy, PH group was given the PH while the 654-2 group was given anisodamine. The heart rate, blood pressure, central venous pressure, gurgling sound, urine output, SPaO2, duration of peripheral warming, serun lactic acid were measured and compared at 1,6,12 h after medication. Resuits All the above mentioned indexes in the PH group were siguifieandy better than those in the 654-2 group. Conclusion The antishoek effect of PH is better than that of anisodamine.