清热退黄口服液治疗慢性乙型病毒性肝炎40例临床研究

Effect of Qingretuihuang oral liquid on the treatment of chronic virus hepatitis B

目的观察清热退黄口服液治疗慢性乙型病毒性肝炎(以下简称乙肝)的疗效。方法将80例乙肝患者随机分成2组,均予门冬氨酸钾镁注射液静脉滴注和维生素C口服治疗。治疗组40例加用清热退黄口服液,对照组40例加用垂盆草冲剂。2组均1个月为1个疗程,治疗2个疗程后观察肝功能、乙肝病毒DNA定量(HBV-DNA)和临床疗效。结果 2组治疗后丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、血清总胆红素(TBiL)均较本组治疗前降低(P<0.01),治疗组治疗后ALT、AST低于对照组(P<0.01)。治疗组总有效率92.5%,对照组总有效率72.5%,2组总有效率比较差异有统计学意义(P<0.05),治疗组疗效优于对照组。结论清热退黄口服液治疗乙肝有显著疗效,优于常用药物垂盆草冲剂。

Objective To evaluate the effect of Qingretuihuang oral liquid on the treatment of chronic virus hepatitis B.Methods 80 patients with chronic virus hepatitis B were randomly divided into two groups.Patients in two groups were treated by intravenous drip of Potassium-magnesium aspartate injection and oral vitamin C.And patients in control group were treated by Chuipencao granule.Patients in treatment group were treated by Qingretuihuang oral liquid.The course was ten days in two groups.Liver function,HBV-DNA and effect were observed.Results ALT,AST and TBiL after treatment were decreased in comparison with those before treatment in two groups（P0.01）.ALT and AST in treatment group were lower than those in control group（P0.01）.The total effective rate in treatment group（92.5%） was higher than that in control group（72.5%,P0.05）.Conclusion Qingretuihuang oral liquid has a significant effect on chronic virus hepatitis B,and the effect was superior to that of Chuipencao granule.