摘要
采用酶联免疫法测定83例高血压患者的尿视黄醇结合蛋白(RBP),同时测定尿N-乙酰氨基葡萄糖苷酶(NAG)、尿微量白蛋白(MALB)及β2微球蛋白(β2-MG)。结果发现高血压患者尿RBP均较正常对照组高,并随病期的延长有逐渐增高的趋势。尿RBP与MALB、NAG、β2-MG呈正相关。提示在高血压早期阶段,肾小管功能会受到损害,尿RBP可作为诊断高血压早期肾损害的敏感指标之一。
TheconcentrationofRBPinurineof83hypertensioncaseswasmeasuredbyELISATheconcentrationofNacetylbetaDglucosamindase(NAG)microalbumin(MALB)2microglobulin(2MG)inurinewerealsomeasuredWefoundthattheurineRBPinallhypertensioncaseswassignificantlyhigherthanthatincontrolgroupTheconcentrationofRBPgraduallyincreasedwiththedevelopmentofhypertensionTheurineRBPwasrelatedpositivelytourineMALBNAG2MGConclusionrenaltubularfunctionhasbeendamagedinearlyhypertension,andurineRBPisanindicatorofdiagnosisoftheearlyrenaldamageinhypertension
出处
《山东医药》
CAS
北大核心
1999年第14期11-12,共2页
Shandong Medical Journal