外周动脉疾病相关危险因素的临床分析

THE CLINICAL ANALYSIS OF RISK FACTORS ABOUT PERIPHERAL ARTERIAL DISEASE

目的比较高血压合并代谢综合征(MS)、高血压、MS三组群体PAD发病率及PAD发生相关危险因素。方法连续选取2005年1月～2010年1月在我院确诊符合高血压合并MS、高血压、MS诊断标准的三组群体共1982例。其中男女之比861:1121,平均(59.2±7.3)岁,平均血压(151±15)/(91±10)mmHg。随访中行踝臂指数(ABI)测量并做动态监测。分析三组群体PAD发病率及高危因素。结果高血压合并MS组PAD发病率(35.12%)与高血压组PAD发病率(21.04%)及MS组PAD发病率(22.15%)比较有明显差异,且差异有高度统计学意义(p<0.01)。在高血压合并MS患者中,PAD组高脂血症、冠心病、糖尿病、吸烟明显高于无PAD组(p<0.01)。吸烟、糖尿病、血脂异常、高血压危险因素与PAD的发生相关。结论高血压合并MS组PAD发生率高于高血压组和MS组。PAD与发生主要心血管事件的危险密切相关。

Objective To compare the morbidity of peripheral artery disease（PAD） among three groups of patients：patients affected with Hypertension and metabolic syndrome（MS）（Group A）,patients affected with hypertension（Group B）,and patients affected with MS（Group C） as well as compare the related risk factors which cause PAD.Methods Continuously select a total of 1982 cases from three groups respectively who diagnosed with hypertension and MS,Hypetension,MS in our hospital during 2005.1-2010.1,with the male female ratio of 861：1 121,mean age（59.2±7.3） years,mean blood pressure（151±15）/（91±10）mmHg.Do ABI measurement and dynamic monitoring,analyze the incidence and risk factors of PAD of these three groups.Results There are obvious differences among the morbidity of PAD among these three groups of patients.The morbidity is respectively 35.12%,21.04% and 22.15%.The difference is of great significance in terms of statistics.It is found that hyperlipidemia,coronary heart disease,diabetes,smoking is the related risk factors that cause PAD and that the morbidity of hyperlipidemia,coronary heart disease,diabetes,and smoking in Group A is the highest.Conclusion Among the three groups,morbidity of PAD in Goup A is the highest and cardiovascular events are highly related to PAD.