坚持使用避孕套情况下的夫妻间艾滋病病毒感染因素分析

A case report of heterosexual transmission of HIV infection between spouses with persistent condom use

目的 避孕套干预对夫妻间艾滋病病毒（ＨＩＶ） 传播的作用。方法 为首例ＨＩＶ感染者建立个人档案，固定流行病学医师对感染者和配偶每６ 个月进行一次ＨＩＶ抗体检测和家庭随访，ＨＩＶ抗体检测采用ＥＬＩＳＡ、ＰＡ、ＷＢ法，阳性结果由山东省卫生防疫站确认。结果 首例男性１９９２ 年入境时确认ＨＩＶ感染。卫生防疫人员立即对感染者夫妇进行了预防ＡＩＤＳ教育。几年来配偶间性接触均使用避孕套，但使用前未进行破损检查。其配偶１９９７ 年５ 月曾出现不明原因低热１月余，同年８ 月在第１４ 次检测时阳性，并确认为ＨＩＶ－ １ 型感染。结论 使用避孕套可在较长时间内预防ＨＩＶ经性接触感染，但不正确使用仍可造成ＨＩＶ感染。

Objective To report a case of heterosexual transmission of HIV infection between spouses with consistent condom use. Methods The first case with HIV infection was detected in the contracted male workers returned from abroad in Qingdao in 1992 and both he and his spouse were given health education for AIDS/HIV prevention and instructions on condom use. And,his wife was followed- up every six months by detecting her serum anti-HIV. Results The wife of the index case was negative for anti-HIV in the first 12 blood tests before December 1996. But, she was found suspect of positive for anti-HIV in July 1997 and definitely positive for anti-HIV-1 in August 1997 during her 14th test. In the period of 1992 to 1997,they persisted in condom use during intercourse. Recall of the wife showed that she had low fever in May 1997, suggesting at the window phase of her acute HIV infection. It postulated that she infected with HIV during March to April 1997. Conclusion The case report indicated that incorrect use of condom could not prevent from HIV transmission between spouses.