商丘市中心医院药品不良反应102例分析

Analysis of adverse drug reaction report in our,Hospital 102 cases

目的分析药品不良反应(ADR)的情况及发生特点,为临床安全用药提供参考。方法对商丘市中心医院2004年1月—2009年12月发生的102例药品不良反应(ADR)进行回顾性分类与统计分析。结果 102例ADR共涉及药品48种,静脉给药途径所引发的ADR最多,抗感染药占38.24%;中药制剂占30.40%。结论抗感染药、中药制剂ADR的发生率高。提醒临床应密切关注药品ADR,加强药品ADR的监测与上报工作,合理规范使用药物,减少ADR的发生率。

Objective To analyze the general state of health of ADR cases and the features of adverse drug reactions（ADR） in our hospital for clinical references and safe drug use.Methods Totally 102 ADR cases collected from Jan.2004 to Dec.2009 in our hospital were analyzed retrospectively.Result A total of 48 drugs were involved in the 102 ADR,the high incidence of ADR were caused by intravenously,mainly anti-infective drugs（38.24%）,followed by traditional Chinese materia medica preparation（30.40%）.Conclusions The ADR were mainly induced by the use of anti-infectives and Chinese material medica preparation ADR monitoring and reporting work should be strengthened to ensure safe,and rational drug use in the clinic,so as to lessen the occurrence of ADR.