中西医结合治疗早期糖尿病肾病的观察

Integrative Medicine in early diabetic nephropathy

目的观察中西医结合治疗早期糖尿病肾病(DN)的临床疗效。方法将60例早期DN患者随机分为治疗组和对照组各30例,两组血糖水平均控制良好,同时积极控制血压,对照组用替米沙坦治疗,治疗组在上述治疗的基础上结合中医辩证治疗。结果两组治疗前后血糖、血脂比较有统计学意义(P<0.05),但治疗后两组间比较无统计学意义(P>0.05)。治疗前后尿白蛋白排泄率、尿α1微球蛋白变化有统计学意义(P<0.05),治疗组较对照组下降更明显(P<0.05)。结论中西医结合治疗早期糖尿病肾病效果好,值得推广应用。

Objective To observe the clinical efficacy of the treatment of early diabetic nephropathy with Integrative Medicine（DN）.Methods Totally 60 patients with early DN were randomly divided jnto treatment group and control group 30 cases,two groups of blood glucose levels were well controlled,while actively controlling blood pressure in the control group treated with telmisartan treatment group on the basis of the above treatment dialectical combination of traditional Chinese medicine treatment.Results Both berore and after treatment blood glucose,blood lipids was statistically significant（P0.05）,but after treatment between the two groups was not significant（P0.05）.Before and after treatment of urinary albumin excretion rate,urinary α1-microglobulin change significantly（P0.05）,the treatment group decreased more significantly than the control group（P0.05）.Conclusions Integrative treatment of early diabetic kidney disease is effective,and should be widely applied.