无创正压通气治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭45例分析

Analysis of noninvasive positive pressure ventilation in chronic obstructive pulmonary disease with type Ⅱ respiratory failure 45 cases

目的探讨无创正压机械通气治疗慢性阻塞性肺疾病(COPD)合并Ⅱ型呼吸衰竭的疗效。方法选择近年来收治的COPD合并Ⅱ型呼吸衰竭患者90例,随机分为治疗组和对照组,两组均给予常规抗感染、解痉平喘、祛痰、能量支持等常规治疗,对照组予低浓度氧疗,治疗组采用面罩BIPAP呼吸机治疗。观察两组患者临床症状、生命体征、血气分析变化。结果 BiPAP治疗组患者临床症状、体征和血气指标在治疗后较治疗前明显改善(P<0.05),两组治疗后的血气指标比较有统计学意义(P<0.05)。结论 BiPAP通气支持治疗COPD合并呼吸衰竭疗效显著。

Objective To investigate the effect of non-invasive positive pressure ventilation treatment of chronic obstructive pulmonary disease（COPD） with type Ⅱ respiratory failure.Methods COPD admitted to our hospital in recent years,respiratory failure patients with type Ⅱ 90 patients were randomly divided into treatment group and control group were given conventional anti-inflammatory,antispasmodic antiasthmatic,expectorant,energy support conventional treatment,the control group to the low concentration of oxygen therapy in the treatment group with BIPAP mask ventilation in the treatment.Observation of clinical symptoms,vital signs,blood gas changes analysis.Results BiPAP treatment group,clinical symptoms,signs and blood gas analysis after treatment than before treatment significantly improved（pH,PaO2,PaCO2,P values were 0.05）,two grokps of blood gas analysis was statistically significant（The P values were 0.05.Conclusions BiPAP ventilatory support treatment of COPD with respiratory failure has a significant effect.