食管癌术后呼吸功能不全的危险因素分析

Retrospecitive study on the risk factors of postoperative respiratory dysfunction in patients with esophageal carcinoma

目的探讨食管癌术后并发呼吸功能不全的危险因素及其预防。方法对108例食管癌术后呼吸功能不全患者的临床资料做回顾性分析,并对可能的危险因素进行logistic回归分析。结果在本研究中,食管癌术后并发呼吸功能不全的发生率为10.06%。在这108例食管癌术后并发呼吸功能不全的患者中,平均年龄62岁,平均体质量指数24.13 kg/m2,肺功能评估FEV1/FVC<0.7的患者23例,低蛋白血症35例,术后吻合口瘘21例。结论高龄、肥胖、吸烟史、低蛋白血症、术前肺部基础疾病致肺功能下降(FEV1/FVC<0.7)、术后吻合口瘘等是食管癌术后呼吸功能不全的主要危险因素。

Objective To study the risk factors of postoperative respiratory dysfunction in patients with esophageal carcinoma. Methods Retrospecitive analysis was performed on clinical data of 108 patients with respiratory dysfunction after esophageal carcinoma resection . Results In this series,postoperative respiratory dysfunction developed in 108 of 1074（10.06%）. Among 108 patients with postoperative respiratory dysfunction,the average age was 62 year, the average BMI was 24.13 kg/m2,23 cases＇ lung function test index（FEV1/FVC）was less than 0.7,35 cases were with hypoalbuminemia and 21cases with anastomotic leak. Conclusion The main factors causing postoperative respiratory dysfunction in patients with esophageal carcinoma are as follows：age, obesity,smoking history,hypoalbuminemia,poor preoperative lung function,anastomotic leak.