棉酚对奶牛胎儿发育毒性的研究

The research of developmental toxicity for gossypol on dairy cow fetus

用棉酚含量４．０ ｇ／ｋｇ 的棉籽饼以每头０．５ ｋｇ／ｄ 饲喂怀孕奶牛３５ ｄ，研究棉酚对奶牛胎儿发育的影响。结果表明，在开始饲喂后１４～４６ ｄ 的流产率为９．１％ （１７／１８６）；中毒的妊娠奶牛平均怀孕期为（２７５．７５±５．２１） ｄ （ｎ＝ １４０），其所产的犊牛平均初生质量为（３５．２７±５．２３） ｋｇ （ｎ＝ １４０），与１９９１ 和１９９３ 年同期相比较，平均怀孕期缩短２～３ ｄ，初生犊牛平均质量降低３．７０ ｋｇ；活产母犊到６ 月龄和２４ 月龄时，淘汰率分别为３９．７％ （２７／６８）和８５． ３％ （５８／６８），６ 月龄时平均质量为（１４６．６±３３．８） ｋｇ （ｎ＝ ４５），平均日增质量为（０．６２±０．２０） ｋｇ （ｎ＝ ４５），分别比１９９１ 和１９９３ 年的平均值降低３４．５ 和０．１７

It will exert a great influence on the growth and development of dairy cow fetus if feeding pregnant dairy cow for 35 days with cottonseed cake 0.5 kg per day containing 4 g/kg gossypol. The rate of abortion were 9.1% (17/186) during 14-46 days after beginning feed. The average gestation period of calves born by pregnant cow of gossypol poisoning was (275.75±5.21) days ( n =140),2-3 days shorten than that of the year of 1991 and 1993, and the average newborn weight of calves was (35.27±\{5.23\}) kg ( n =140),3.70 kg lower than that of the year of 1991 and 1993.The rate of elimination of living female calves after birth were 39.7% (27/68) and 85.3% (58/68) during 6 month and 24 month respectively due to death,diseases or slow growth and development.The average weight of female calves on 6 month was (146.6±33.8) kg (\{ n =45\}),and the average increased weight per day was (0.62±0.20) kg (\{ n =45\}),reduced 34.5 kg and 0.17 kg than that of the year of 1991 and 1993 respectively.