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胰岛素鼻腔给药研究进展 被引量:1

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摘要 根据胰岛素(INS)是目前治疗胰岛素依赖型糖尿病(ID-DM)的主要药物,属多肽类药物,分子量大,半衰期短,脂溶性差,不易透过生物膜,长期以来一直以注射给药为主,不仅用药不便而且会出现注射部位炎症,硬结等不良反应及耐药性,为此,国内外学者一直致力于INS非注射给药剂型的开发与研制,如鼻腔给药途径,现综述如下。
作者 林润好
出处 《现代医药卫生》 2011年第8期1189-1190,共2页 Journal of Modern Medicine & Health
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  • 1徐培红,陈宇红,王卫庆,姜蕾,李光伟,田浩明,胡仁明,郑宝忠,宁光.胰岛素粉雾剂与注射剂治疗2型糖尿病的随机对照临床研究[J].中国新药与临床杂志,2007,26(9):659-663. 被引量:6
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