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妊娠相关血浆蛋白-A与妊娠期高血压疾病关系的研究 被引量:1

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摘要 目的通过检测妊娠高血压疾病患者外周血妊娠相关血浆蛋白-A(PAPP-A)的浓度,探讨血清妊娠相关血浆蛋白-A与妊娠期高血压疾病发病的关系。方法采用酶联免疫吸附试验(ELISA)法测定70例妊娠期高血压疾病患者(病例组)及70例正常孕妇(对照组)血清PAPP-A含量。结果病例组患者血清PAPP-A与对照组比较,差异有显著意义(P<0.05)。且随病情加重,有逐渐增高的趋势。结论血清PAPP-A与妊娠期高血压疾病发病存在相关关系。
作者 许小莉
出处 《齐齐哈尔医学院学报》 2011年第1期26-27,共2页 Journal of Qiqihar Medical University
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  • 1乐杰.妇产科学[M].第6版.北京:人民卫生出版社,2005.262.
  • 2Bonno M, Oxvig C, Kephart GM, et al. Localization of pregnancy -associated plasma protein-- Ames senger ribonucleic acid and eosinophil granule major basic protein mess enger ribonueleic acid in placent a[J]. Lab In - vest, 1994,71 (4) : 560-566.
  • 3Zh ab in SG,Gorin VS,Judin N S. Immunomodulat or yaetivity of pregnancy- associat ed plasma protein- A[J]. J C lin Lablmm un ol,2003,52:41-50.
  • 4Fialova L, Malbohan IM. Pregnancy associated plasma protein A (PAPP-A) :theoretical and clinical aspects[J]. Bratisl Lek Listy,2002,103(6) : 194-205.
  • 5吕英璞,张文真.妊娠相关血浆蛋白A与妊娠高血压综合征[J].国外医学(妇幼保健分册),2004,15(4):229-231. 被引量:6
  • 6Lawrence JB, Oxvigc, Overgaard MT, et al[J]. Proc Natl Acad Sci USA,1999,96..3 149-3 153.
  • 7Noll K,Wegmann BR, Havemenn K,et al[J].J Clin Endicrinal Meta,1996,81:2 653-2 662.
  • 8Han V KM, Basset t N,Walton J, et al[J]. JClin Endocrinal Metab,1996,81:2 680-2 693.
  • 9Bersinger, Smaras on, Muttukri shna, et al. Women with pre- eelampsia have increased serum levels of pregenacy- associatedplasma protein- A( PAPP- A),inhibin A, activin A and solu- ble E- select in[J]. Hypertens- Pregnancy, 2003,22 ( 1 ) : 45 - 55.

二级参考文献16

  • 1Mashiach R, Orr U A, Yaron Y. A comparison between maternal serum free beta-human chorionic gonadotrophin and pregnancy-associated plasma protein A levels in first-trimester twin and singleton pregnancies [ J ]. Fetal Diagn Ther, 2004,19(2) :174 - 177.
  • 2Mueller M D, Raio L, Spoerri S, et al. Novel placental and nonplacental serum markers in ectopic versus normal intrauterine pregnancy [ J ]. Fertil Steril, 2004,81 (4): 1106 -1111.
  • 3Kwik M, Morris J. Association between first trimester maternal serum pregnancy associated plasma protein-A and adverse pregnancy outcome[J]. Aust N Z J Obstet Gynaecol,2003,43(6) :438 - 442.
  • 4Wapner R, Thom E, Simpson J L, et al. First-trimester screening for trisomies 21 and 18[J]. N Engl J Med,2003,349(15) :1471 - 1473.
  • 5Cheng C C, Lee F K, Lin H W, et al. Diagnosis of fetal acrania during the first trimester nuchal translucency screening for Down syndrome[J]. Int Gynaecol Obstet,2003,80(2) :139 - 144.
  • 6Schuchter K, Hafner E, Stangl G, et al. The first trimester ' combined test ' for the detection of Down syndrome pregnancies in 4939 unselected pregnancies[J]. Prenat Diagn, 2002,22(3) :211 - 215.
  • 7Dumps P, Meisser A, Pons D, et al. Accuracy of single measurements of pregnancy-associated plasma protein-A,human chorionic gonadotropin and progesterone in the diagnosis of early pregnancy failure[J]. Eur J Obstet Gynecol Reprod Biol,2002,100(2): 174 - 180.
  • 8Smith G C, Stenhouse E J, Crossley J A, et al. Early pregnancy levels of pregnancy-associated plasma protein a and the risk of intrauterine growth restriction, premature birth, preeclampsia, and stillbirth [ J ]. Clin Endocrinol Metab,2002,87(4) :1762- 1767.
  • 9Ong C Y, Liao A W, Spencer K, et al. First trimester maternal serum free beta human chorionic gonadotrophin and pregnancy associated plasma protein A as predictors of pregnancy complications [ J ]. BJOG, 2000, 107 ( 10 ): 1265 -1270.
  • 10Bersinger N A, Groome N, Muttukrishna S. Pregnancyassociated and placental proteins in the placental tissue of normal pregnant women and patients with pre-eclampsia atterm[J]. Eur J Endocrinol,2002,147(6) :785 - 793.

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