摘要
目的:探讨类风湿关节炎合并肺间质病变(RA-ILD)的发病年龄、平均病程及各种实验室指标的表达水平,分析RA-ILD发病的相关因素。方法:回顾2007年1月至2010年12月住院的141例类风湿关节炎患者的发病年龄、平均病程及实验室指标,分析RA-ILD患者的特点。结果:61例RA-ILD患者占全部RA患者的43.3%,RA-ILD组在发病年龄、平均病程及C反映蛋白(CRP)、抗核抗体(ANA)、抗环瓜氨酸抗体(抗CCP抗体)方面均高于RA-非ILD组,差异有统计学意义(P<0.05)。结论:对RA患者,尤其是年龄较大、病程较长以及血清ANA、抗CCP抗体阳性和CRP高表达的患者,应尽早做肺部高分辨CT及肺功能测定,以早诊断和治疗肺部病变。
Objective：To explore the age,course and serum markers of rheumatoid arthritis interstitial lung disease（RA-ILD）,and to analyze the related factors involved in the disease.Methods： The age of onset,course,and levels of serum markers were analyzed retrospectively in 141 patients with RA from January of 2007 to December of 2010.Results： Sixty one patients with RA-ILD accounted for 43.3 % of total patients.The age of onset,course and the serum levels of CRP,ANA and anti-CCP antibody in patients with RA-ILD were significantly higher than in patients with non-RA-ILD.Conclusions： HRCT and pulmonary function test should be done to get earlier diagnosis and treatment of ILD in patients with RA,especially in the elder patients with long course and high titer of CRP,ANA and anti-CCP antibody
出处
《包头医学院学报》
CAS
2011年第2期47-49,共3页
Journal of Baotou Medical College
关键词
类风湿关节炎
肺间质病变
Rheumatoid arthritis
Interstitial lung disease
