中药配合西医三联疗法治疗十二指肠球部溃疡89例疗效观察

Clinical Effect of Chinese Medicine with Western Medicine Triple Therapy on the Treatment of 89 Duodenal Ulcer Patients

目的:观察中药配合西医三联疗法(雷贝拉唑联合阿莫西林、克拉霉素)治疗十二指肠球部溃疡的临床疗效。方法:将176例十二指肠球部溃疡患者随机分为2组,治疗组89例采用中药(甘草、白芍、半夏、黄连、桂枝、当归、丹参、延胡索、海螵蛸、三七等)配合西医三联疗法治疗;对照组89例单予西医三联疗法治疗,停药4周后复查胃镜及14碳一尿素呼气试验(14 CUBT),观察溃疡愈合情况以及幽门螺杆菌根除率。结果:治疗组及对照组幽门螺杆菌根除率及十二指肠球部溃疡愈合率分别为98.9%、88.8%和96.7%、85.7%。2组比较有显著性差异(P<0.05)。结论:中药配合西医三联疗法治疗十二指肠溃疡疗效较好。

Objective:To observe the clinical effect of traditional Chinese medicine with Western medicine triple therapy(rabeprazole combined amoxicillin,clarithromycin) on the treatment of duodenal ulcer patients.Methods: 176 patients with duodenal ulcer were randomly divided into 2 groups.89 patients in the treatment group were treated with Chinese herbs(Licorice root,white peony root,Pinellia,berberine,Gui,Angelica sinensis,Salvia,Corydalis,cuttlebone,Panax.etc.) combined with Western triple therapy whereas the 89 patients in the control group were simply with Western triple therapy.A review of endoscopy and 14 C urea breath test(14 CVBT) was conducted to observe Ulcer healing and Helicobacter pylori eradication rate 4 weeks after drug withdrawal.Results: The helicobacter pylori eradication rates and duodenal ulcer healing rates of the treatment group and the control group were 98.9%,88.8% and 96.7%,85.7% respectively.The comparison of 2 groups showed significant difference(P<0.05).Conclusion: The traditional Chinese medicine combined the western triple therapy has a better effect on the duodenal ulcer patients.