子宫颈上皮内瘤变患者行宫颈环切术对妊娠结局的影响

The effects of loop electrosurgical excision procedure (LEEP) on pregnancy and delivery outcomes of patients with cervical epithelial neoplasia(CIN)

目的探讨对宫颈上皮内瘤变患者行宫颈环切术对妊娠结局的影响。方法回顾性分析2001年5月～2010年4月对宫颈上皮内瘤变患者行宫颈环切术27例患者的妊娠结局。结果占同期宫颈环切术宫颈环切术手术的13.3%(27/203),患者年龄为23～40岁,中位年龄为30.3岁。27例中,10例因计划生育行人工流产术、1例异位妊娠、2例6～8周自然流产。14例足月分娩,其中阴道分娩9例,剖宫产5例。所有分娩孕妇的分娩孕周均大于38周,新生儿体重2905～4000g。新生儿1minApgar评分:9分2例;10分12例。无新生儿窒息。结论宫颈环切术是治疗宫颈上皮内瘤变的安全有效的方法。只要掌握手术指征和手术切除范围,对其后的妊娠生育是安全的。

Objective：To investigate in effects of loop electrosurgical excision procedure（LEEP）on pregnancy and delivery outcomes of patients with cervical epithelial neoplasia（CIN）.Methods：The delivery data of 27 pregnant women who had LEEP from May 2001 to April 2010 were retrospectively collected and analysed.Results：The mean age of the 27 women was 30.3 years（range 23～40 year）：Ten women underwent artificial abortion.One entopic pregnancy and two spontaneous miscarriages occurred at 6 to 8 weeks of gestation.There were 14 term pregnancies,9 of them via vaginal delivery and 5 via caesarean section.The birth weight of newborns ranged from 2905 to 4000g.All of newborns had a high Apgar score.No asphyxia occurred.Conclusions：LEEP is a safe and effective treat mean for patients with CIN.It will not increase the risk pregnancy and delivery of the patients.