抗癌药物3——苯基——3——氮桥环三氧化锗基丙酸的合成及分析

The Synthesis and Analysis of a New Antitumor Agent 3-Phenyl-3-Nitrogen Bridgecyclo Trioxidegermyl Propionic Acid

从原料锗氯仿与肉桂酸开始合成了３ —苯基—３ —氯锗基丙酸、３ —苯基—３ —三甲氧基锗基丙酸及３ —苯基—３ —氮桥环三氧化锗基丙酸．用 Ｉ Ｒ，１ Ｈ Ｎ Ｍ Ｒ 及１３ Ｃ Ｎ Ｍ Ｒ

From the raw material trichlorogermane,three compounds------3-phenyl-3-trichlorogermyl propionic acid,3-phenyl-3-trimethyloxygermyl propinic acid,3-phenyl-3-nitrogen bridgecyclo trioxygermyl propionic acid were prepared.The structures of the above compounds were convinced by IR and 1 HNMR 13CNMR spectroscopy.