再灌注损伤对低血容量性休克的创伤病人预后影响

Outcome after Hypovolemic Shock in Trauma Patients of Reperfusion Injury

目的：确定创伤所致的低血容量性休克病人预后与再灌注损伤的关系。方法：选择一组院前或急诊室测量收缩压低于１２ｋＰａ 的创伤患者，比较再灌注迟早及再灌注量对其死亡及发生器官衰竭的影响。结果：１２６ 例中低血容量性休克病人１１８例，在１５ｍ ｉｎ～４ｈ 内建立静脉通道。再灌注迟者死亡率及器官衰竭较再灌注早者高。大量晶体液的灌注导致死亡率升高。结论：缺血时间越长导致再灌注的损伤明显加重。且随着晶体液的灌注增多死亡率增高。

Objective: To identify the relationship of hypovolemic shock and reperfusion injury. Methods: We select a group of patients in trauma whose systolic blood pressure≤12kPa in the field or in the emergency department. The volume of reperfusion and the variety of reperfusion are associated with the ratio of death and organ failure. Results: Among the 126 patients with hypovolemic shock 118 patients get the intravenous drip in 4 hours after injury. The later intravenous drops drip to patients, the more patients are died and organ failure. Large volumes of crystalloid reperfusion will increase the motility and organ failure. Conclusion: Adjourned the hypoemia time induced more serious of reperfusion injury. Increasing volume of crystalloid was strongly associated with increased mortality and organ failure.