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奥沙利铂神经毒性的预防和处理的中西医研究进展 被引量:12

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摘要 奥沙利铂(草酸铂,L-OHP)是继顺铂和卡铂之后的第3代铂类广谱抗癌药,它以1,2一二氨环已烷基团(DACH)取代了顺铂的氨基,药学特性得到了改善,其疗效更好,毒性更低,能更有效的抑制DNA复制。在临床前和临床研究中,L-OHP对许多不同类型的肿瘤都显示出抗瘤活性[1],
出处 《临床合理用药杂志》 2011年第5期59-62,共4页 Chinese Journal of Clinical Rational Drug Use
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