齿叶白鹃梅叶化学成分研究

Study on Chemical Constituents of Leaves of E.Serratifolia S.Moore

目的：研究齿叶白鹃梅叶的化学成分。方法：采用硅胶柱色谱、重结晶和Sephadex LH-20凝胶柱色谱的方法进行化学成分的分离和纯化,根据化合物的理化性质和波谱数据鉴定其结构。结果：分离得到化合物6个,经鉴定为β-谷甾醇（Ⅰ）、十八碳酸单甘油酯（Ⅱ）、齐墩果酸（Ⅲ）、熊果酸（Ⅳ）、原儿茶酸（Ⅴ）、胡萝卜苷（Ⅵ）。结论：化合物Ⅰ-Ⅵ均首次从此植物中分离得到。

Objective：To study the chemical constituents of the leaves of E.serratifolia S.Moore.Method：Isolation and purification were carried out on the chromatography of silica gel and Sephadex LH-20.Their structures were elucidated on basis of physicochemical properties and spectral data.Result：Six compounds were isolated and identified asβ-sitosterol（Ⅰ）,glycerol mono stearol acid（Ⅱ）,oleanolic acid（Ⅲ）,ursolic acid（Ⅳ）,protocatechuic acid（Ⅴ）,daucosterol（Ⅵ）.Conclusion：Compounds Ⅰ~Ⅵ are isolated from this plant for the first time.