慢性移植肾肾病的发病机制及中医药治疗进展

Recent Progress in Research on Pathogenesis and Treatment with Traditional Chinese Medicine of Chronic Allograft Nephropathy

肾移植是治疗终末期肾病的有效方法,临床上主要通过运用和调整免疫抑制剂来改善预后,但肾移植患者长期存活率仍然不到50%。慢性移植肾肾病是导致移植肾晚期功能丧失的最主要原因,该病目前缺乏有效的治疗手段。文章从慢性移植肾肾病的发病机制出发,结合目前中医药治疗该病的现状,探求治疗慢性移植肾肾病更有效的方法。

Renal transplantation is an effective method for the terminal stage of nephrosis.Despite improvements in immunosuppressive therapy,long-term allograft survival after kidney transplantation remains as low as 50%.Chronic allograft nephropathy（CAN）is a major cause of late grafts loss in renal transplant recipients.For the cause of CAN is complex and incompletely understood,there is lack of utility in therapy of the disease.Inorder to give more effective therapy,this text presents the pathogenesis and current situation in treatment with traditional Chinese medicine of CAN.