灵芝多糖的生物合成和发酵调控

Biosynthesis and fermentation control of polysaccharides from Ganoderma lucidum

灵芝多糖是灵芝的关键药效成分之一。从灵芝多糖的结构和构效关系、灵芝多糖的单糖组成,灵芝主要多糖IPS-1-1的基本合成途径,以及灵芝多糖的深层发酵调控策略和方法等方面,综述了灵芝多糖生物合成和发酵调控方面的新进展。并对今后的主要研究方向进行了展望。

Ganoderma lucidum polysaccharides（GPS） are of the key pharmacologically active components of this medicinal fungus.Structure-activity relationship,constituents of monosaccharides of GPS,and basic biosynthetic pathways of the key GPS,IPS-1-1,as well as strategies and methods of fermentation control of GPS were reviewed.Further,future orientation in development of biosynthesis and fermentation control of GPS was discussed.