角膜生物参数对青光眼患者眼压测量影响的研究

Influence of corneal biomechanical properties on intraocular pressure measurements of the glaucoma patients

目的:探讨角膜生物参数对青光眼患者眼压测量的影响。方法:对80例121眼青光眼患者进行眼反应分析仪(ocular response analyzer,ORA)与Goldmann压平眼压计(Goldmann applanation tonometer,GAT)测量,并用先进的OrbscanⅡ眼前节分析系统测量中央角膜厚度(central corneal thickness,CCT)。结果:平均矫正眼压(IOPcc)值17.41±5.62mmHg;平均GAT值15.76±6.06mmHg;IOPcc与角膜滞后性(cornealhysteresis,CH)有相关性(P=0.000;r=-0.236);IOPcc与GAT显著相关(P=0.000;r=0.857);IOPcc与CCT无相关性。结论:对已经诊断的青光眼患者,平均IOPcc值高于平均GAT值;随着CH的降低,IOPcc值有升高的趋势;且IOPcc值不受CCT值的影响。

AIM：To evaluate the influence of corneal biomechanical properties on intraocular pressure（IOP）measurements of the glaucoma patients.METHODS：The study included 121 eyes of 80 cases.All cases underwent IOP evaluation with the ocular response analyzer（ORA）and Goldmann applanation tonometry（GAT）,and central corneal thickness（CCT）was measured with Orbscan Ⅱ.RESULTS：The mean IOPcc was 17.41±5.62mmHg;the mean GAT was 15.76±6.06mmHg.IOPcc was significantly associated with corneal hysteresis（CH）and GAT（P=0.000）;IOPcc was not associated with CCT.CONCLUSION：For glaucoma patients,the mean IOPcc is higher than the mean GAT.The IOPcc tends to be higher,while the CH is lower.The IOPcc is not influenced by CCT.