FQ-PCR检测女性泌尿生殖道炎性反应患者解脲脲原体合并感染情况分析

Analysis on the FQ-PCR detection of female patients with urogenital tract infection and ureaplasma urealyticum co-infection

目的分析女性泌尿生殖道炎性反应患者解脲脲原体(Uu)合并感染淋球菌(NG)、沙眼衣原体(CT)的情况,用以指导临床进行正确的诊断和治疗。方法采用TaqMan探针荧光定量PCR技术,对205例女性泌尿生殖道炎性反应患者进行Uu、NG和CT检测。结果在205例女性泌尿生殖道炎性反应患者中检测出Uu感染率为52.68%(108/205),NG和CT感染率均为1.46%(3/205),并且女、男单项和混合感染率比较差异有统计学意义(P<0.05)。结论在女性泌尿生殖道炎性反应患者中Uu有较高的感染率,但对拟诊为Uu的患者应同时进行NG、CT检测,以免由于漏检而延误患者治疗。

Objective To analyze the infection of ureaplasma urealyticum（Uu）,neisseria gonorrhoeae（NG）and chlamydia trachomatis（CT） of female patients with urogenital tract infection,and to provide an appropriate clinical guide.Methods We used FQ-PCR to detect the Uu,NG and CT from 205 female patients with urogenital tract infection.Results The positive rate of Uu was 52.68%（108/205）,and of NG/CT was 1.46%（3/205）.The single and mixed infection rates between male and female were statistically different（P0.05）.Conclusion Though the positive rate of Uu is the highest compared with those of NG,CT in female patients with urogenital tract infection,we should also detect NG and CT in order to discover the mixed infection and give the patients effective therapy.