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两种香兰素腙类化合物的合成及抑菌活性初步研究 被引量：3

Synthesis and Antifungal Activity of Two Hydrazones Derived from Vanillin
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摘要 以香兰素为原料,与苯肼和对硝基苯肼缩合得到两种香兰素腙类化合物,其结构经1H-NMR、IR表征。初步的抑菌试验表明,这些化合物对大肠杆菌(Escherichia coli)和金黄色葡萄球菌(Staphylococcus aureus)具有一定的抑菌效果。 Reactions of vanillin with phenylhydrazine and 4-nitrophenylhydrazine in methanol or acetic acid resulted in the vanillinphenylhydrazone,and vanillin-4-nitrophenylhydrazone,respectively.These products were identified by IR and 1H-NMR.And the preliminary antifungal experiments indicated that these compounds had some antifungal activity against E.coli and S.aureus.
作者 邹怀波 周蓉 梁辉 南建忠
机构地区 宜春学院江西省天然药物活性成分研究重点实验室 宜春学院江西省高校应用化学与化学生物学重点实验室 宜春学院化学与生物工程学院
出处 《湖北农业科学》 北大核心 2011年第7期1388-1389,1393,共3页 Hubei Agricultural Sciences
基金 江西省宜春市科技支撑计划项目
关键词 香兰素 腙类化合物 合成 抑菌活性 vanillin hydrazone synthesis antifungal activity
分类号 S482.2 [农业科学—农药学]
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参考文献14

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同被引文献30

  • 1汪飞,曹瑾,袁莉萍,郭庆铭,倪长春,沈宙,张一宾.新型腙类衍生物的合成及其生物活性[J].农药学学报,2006,8(2):176-179. 被引量：17
  • 2Shah M,Patel P,Parekh H. Synthesis and biological evaluation of thieno pypimidine derivatives[J].Oriental Journal of Chemistry,2002,(01):159-161.
  • 3EI-Hawash S A,Abdel Wahab A E,EI-Demellawy M A. Cyanoacetic acid hydrazones of 3-(and 4-) acetylpyridine and some derived ring systems as potential antitumor and anti-HCV agents[J].ARCHIV DER PHARMAZIE,2006,(01):14-23.
  • 4Ferreira M L,Goncalves R S B,Cardoso L N. Synthesis and antitubercular activity of heteroaromatic isonicotinoyl and 7 chloro-4-quinolinyl hydrazone derivatives[J].The Scientific World Journal,2010.1347-1355.
  • 5Lee P P F,Poon K K. Copper(Ⅱ) salicylaldehydeN,N-dibenzylsemicarbazone-a potential antitumour compound[J].International Journal of Pharma and Bio Sciences,2011,(04):174-190.
  • 6Zhu Shizheng,Zhu Shifa,Jin Guifang. Strong phenyl-perfluorophenyl π-π stacking and C - H…F-C hydrogen bonding interactions in the crystals of the corresponding aromatic aldimines[J].Tetrahedron Letters,2005,(15):2713-2716.
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  • 10Burgart Y V,Fokin A S,Kuzueva O G. Synthesis of fluorinated 2(3)-arylhydrazones of 1,2,3-tri (1,2,3,4-tetra) carbonyl compounds and their beterocyclization reactions[J].Journal of Fluorine Chemistry,1998,(02):101-108.

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湖北农业科学
2011年 第7期

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