牙体修复性纳米羟基磷灰石复合材料的机械性能研究

Experimental study of dentistry nano-hydroxyapatite composite

目的本研究目的旨在研制一种能达到牙齿仿生学要求并用于牙科修复的生物活性材料。方法将经过硅烷偶联剂KH-570进行表面处理后的纳米羟基磷灰石(Nano-hydroxyapatite,NHA)与配制好的光固化树脂基质共混,制备成复合材料,根据复合材料中NHA所占的不同比例(45wt%、50wt%、55wt%、60wt%)分为A、B、C、D四组,卡瑞斯玛复合树脂为对照组记为E组;测试各组固化深度和抗压强度。结果固化深度随NHA的比例增加而减少,任两组间均有显著性差异;实验组中C组压缩强度和挠曲强度最高,与其他3组差异具有显著性(P<0.05),与对照组比较无显著性差异(P>0.05)。结论 55wt%的NHA作为无机填料制备成的复合材料,其压缩强度和挠曲强度能够达到牙科修复材料的要求,具有进一步的研究和临床应用价值。

Objective To develop a bioactive material that can achieve bionic requirement and be used in dental restoration. Methods Nano-hydroxyapatite（NHA） treated with silane coupling agent KH-570 was mixed with light-curing resin matrix.Then,the composite materials were divided into A,B,C,and D groups based on the proportion of NHA（45wt%,50wt%,55wt%,and 60wt%） in the composite materials,and CHARISMA served as control group was signed E.The five groups were all tested for curing depth and compressive strength with the curing depth tester and universal testing machine. Results The curing depth increases with the reduction of the proportion of NHA,with significant difference between any two groups.The compressive strength and flexural strength were larger in group C than in other three experimental groups,with significant difference observed between them（P0.05）,but no significant difference observed between C group and control group（P0.05）. Conclusion The composite material of 55wt% NHA,as the inorganic filler,could meet the requirements of compressive strength and flexural strength for dental restorative materials,with further research and clinical application value.