胺碘酮联合稳心颗粒转复阵发性心房纤颤的疗效研究

Clinical Research of Amiodarone Combined with Wenxin Grain for Paroxysmal Atrial Fibrillation

目的观察胺碘酮联合稳心颗粒转复阵发性心房纤颤(房颤)的临床疗效。方法将90例阵发性心房颤动的患者随机分为胺碘酮治疗组、稳心颗粒治疗组、胺碘酮和稳心颗粒联合治疗组,每组各30例患者,疗程均为8周。观察3组治疗后的转复率、症状改善情况及不良反应。结果胺碘酮组转复率为50.0%,稳心颗粒组转复率为45.2%,联合治疗组的转复率为80.0%,联合治疗组与单用药物比较差异有统计学意义。胺碘酮和稳心颗粒治疗组症状改善有效率分别为66.7%、56.7%,联合治疗组症状改善有效率76.7%,联合治疗组与单用药物比较差异有统计学意义。结论胺碘酮联合稳心颗粒可提高阵发性房颤的转复率,改善患者症状。

Objective To observe clinical curative effect of amiodarone combined with wenxin grain for paroxysmal atrial fibrillation.Methods Ninety patients with paroxysmal atrial fibrillation were divided into wenxin grain,amiodarone and united group randomly（n=30,each group）.8 weeks after treatment,converting rates、symptoms improved conditions and adverse reactions were observed.Results Converting rates in amiodarone,wenxin grain,and united group were 45.2%、50.0 %、80.0%.United group was higher than amiodarone or wenxin grain.Symptoms improved effective rate in amiodarone,wenxin grain,and united group were 50.8%、55.6%、85.0%.Amiodarone or wenxin grain was lower than united group.Conclusion United group can increase converting rates in paroxysmal atrial fibrillation,improve patients′ symptoms.