昆明地区女性200例慢性湿疹和接触性皮炎斑贴试验结果分析

Analysis of patch test in 200 female patients with chronic eczema and contact dermatitis in Kunming

目的探讨昆明地区女性慢性湿疹和接触性皮炎的变应原分布特点及其相关性。方法对100例慢性湿疹和100例接触性皮炎患者进行斑贴试验。结果斑贴试验显示,慢性湿疹组病人的斑贴试验阳性率为44%,接触性皮炎组病人的斑贴试验阳性率为68%,P<0.01,显示两者之间有显著性差异;湿疹组阳性病例中一种变应原的阳性率为63.57%,两种及以上变应原阳性率为36.43%;接触性皮炎组阳性比例中1种变应原阳性率为82.53%,两种及以上变应原阳性率为17.47%,均有统计学差异(P<0.05)。结论斑贴试验有助于明确慢性湿疹和接触性皮炎患者的接触变应原,其主要变应原不尽相同。

Objective To explore the allergen characteristics of chronic eczema and contact dermatitis, and discuss the relationship between these different allergens. Methods 200 patients （ 100 cases with the chronic eczema, and 100 cases with contact dermatitis） were examined by patch testing reagent box, and the standard refered to ICDRG criterion. Results The positive rate was 44% in chronic eczema group, and 66% in contact dermatitis group, with statistically significant difference（P 〈0.01 ）. The positive rate of single allergen in chronic eczema group was 63.57% , and 82.53% in contact dermatitis group; and the positive rate of two or more allergens in chronic eczema group was 36.43% and 17.47% in contact dermatitis group. There was statistically significant difference between two groups （P 〈 0.05）. Conclusion Patch testing is helpful to define the allergens in chronic eczema and contact dermatitis,and the allergens causing two diseases were not the same.