Highly Stereoselective Synthesis of 1,2-Diorganothio-l-alkenes via Hydrothiolation of Alkynyl Sulfides Catalyzed by Cesium Hydroxide 被引量：1

Highly Stereoselective Synthesis of 1,2-Diorganothio-l-alkenes via Hydrothiolation of Alkynyl Sulfides Catalyzed by Cesium Hydroxide

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摘要 In the presence of catalytic amount of cesium hydroxide, the hydrothiolation of alkynyl sulfides occurred at room temperature in DMF under nitrogen atmosphere to afford exclusive （Z）-1,2-diorganothio-1-alkene in excellent yields. It could provide a new and expedient way for the preparation of symmetrical and unsymmetrical （Z）-1,2-diorganolthiol-1-alkenes. In the presence of catalytic amount of cesium hydroxide, the hydrothiolation of alkynyl sulfides occurred at room temperature in DMF under nitrogen atmosphere to afford exclusive （Z）-1,2-diorganothio-1-alkene in excellent yields. It could provide a new and expedient way for the preparation of symmetrical and unsymmetrical （Z）-1,2-diorganolthiol-1-alkenes.

作者谭平尹显洪喻爱和邱仁华彭丽芬许新华赵亚磊唐瑞仁

机构地区 Department of Biological and Chemical Engineering College of Chemistry and Ecological Engineering College of Chemistry and Chemical Engineering College of Chemistry and Chemical Engineering

出处《Chinese Journal of Chemistry》 SCIE CAS CSCD 2011年第4期765-768,共4页 中国化学（英文版）

基金 Project supported by the National Natural Science Foundation of China （Nos. 21071152, 20372020）.

关键词 nucleophilic addition regioselectivity ALKYNES HYDROTHIOLATION cesium hydroxide （Z）-1 2-diorganolthiol- 1-alkenes nucleophilic addition, regioselectivity, alkynes, hydrothiolation, cesium hydroxide, （Z）-1,2-diorganolthiol- 1-alkenes

分类号 TQ463.24 [化学工程—制药化工] O627.61 [理学—有机化学]

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