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A Fast and Highly Efficient Protocol for Reductive Amination of Aromatic Aldehydes Using NaBH4 and Isoxazole Amines in an Ionic Liquid Medium 被引量:3

A Fast and Highly Efficient Protocol for Reductive Amination of Aromatic Aldehydes Using NaBH4 and Isoxazole Amines in an Ionic Liquid Medium
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摘要 Reductive amination of aromatic aldehydes using NaBH4 and isoxazole amines is carried out in a Bronsted acidic ionic liquid 1 -methylimidazolium tetrafluoroborate [(HMIm)BF4]. The ionic liquid plays dual roles of solvent as well as catalyst for the efficixcellent yields without any undesired side product formation. The newly synthesized compoundsent transformation of aromatic aldehydes to heterocyclic substituted amines in e (3, 6 and 7) were characterized by IR, 1H NMR and mass spectral techniques. Reductive amination of aromatic aldehydes using NaBH4 and isoxazole amines is carried out in a Bronsted acidic ionic liquid 1 -methylimidazolium tetrafluoroborate [(HMIm)BF4]. The ionic liquid plays dual roles of solvent as well as catalyst for the efficixcellent yields without any undesired side product formation. The newly synthesized compoundsent transformation of aromatic aldehydes to heterocyclic substituted amines in e (3, 6 and 7) were characterized by IR, 1H NMR and mass spectral techniques.
出处 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2011年第4期769-772,共4页 中国化学(英文版)
关键词 ionic liquid green chemistry reductive amination 1-methylimidazolium tetrafluoroborate isoxazole amine ionic liquid, green chemistry reductive amination, 1-methylimidazolium tetrafluoroborate, isoxazole amine
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